In short

J2312 is the HCPCS Level II code for injection, naloxone hydrochloride, not otherwise specified, 0.01 mg: drugs with no specific code of their own. It has no fixed drug or unit, so the claim carries the NDC of the drug given and its quantity.

Code

CMS HCPCS file
HCPCS codeJ2312
Billing unit0.01 mg
Descriptor
Injection, naloxone hydrochloride, not otherwise specified, 0.01 mg
Short descriptor
Inj naloxone hcl nos, 0.01mg
Code set
HCPCS Level II, maintained by CMS
Effective
Jul 1, 2025

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.076
Per0.01 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Enter the units to build the claim line.

NDCs billed under J2312

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 47 NDCs to J2312 for Naloxone HCl. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J2312 in the CMS ASP crosswalk
DrugNDC (11-digit)LabelerPackageBilling units per package
Naloxone HCl00404-9773-01Henry Schein Inc.140
Naloxone HCl00404-9920-01Henry Schein Inc.140
Naloxone HCl00404-9921-02Henry Schein Inc.2200
Naloxone HCl00404-9922-02Henry Schein Inc.2200
Naloxone HCl00404-9923-01Henry Schein Inc.140
Naloxone HCl00409-1215-01Pfizer Inc10 × 1400
Naloxone HCl00409-1219-01Pfizer Inc25 × 1010,000
Naloxone HCl00409-1782-69Pfizer Inc10 × 1400
Naloxone HCl00641-6132-25Hikma Pharmaceuticals USA Inc.25 × 11,000
Naloxone HCl00641-6193-10Hikma Pharmaceuticals USA Inc.10 × 1400
Naloxone HCl00641-6205-10Hikma Pharmaceuticals USA Inc.10 × 24,000
Naloxone HCl36000-0308-10Baxter Healthcare Corporation10 × 1400
Naloxone HCl36000-0310-02Baxter Healthcare Corporation10400
Naloxone HCl42023-0224-01Endo USA, Inc.2200
Naloxone HCl43066-0142-10Baxter Healthcare Corporation10 × 22,000
Naloxone HCl43598-0750-10Dr. Reddy's Laboratories Inc.10 × 22,000
Naloxone HCl43598-0750-58Dr. Reddy's Laboratories Inc.10 × 22,000
Naloxone HCl50090-3294-00A-S Medication Solutions10 × 1400
Naloxone HCl50090-5427-00A-S Medication Solutions10 × 1400
Naloxone HCl50090-6491-00A-S Medication Solutions10 × 1400
Naloxone HCl51662-1238-01HF Acquisition Co. LLC, DBA HealthFirst140
Naloxone HCl51662-1239-01HF Acquisition Co. LLC, DBA HealthFirst2200
Naloxone HCl51662-1239-03HF Acquisition Co. LLC, DBA HealthFirst10 × 22,000
Naloxone HCl51662-1242-01HF Acquisition Co. LLC, DBA HealthFirst140
Naloxone HCl51662-1242-03HF Acquisition Co. LLC, DBA HealthFirst50 × 12,000
Naloxone HCl51662-1385-01HF Acquisition Co. LLC, DBA HealthFirst10400
Naloxone HCl51662-1586-01HF Acquisition Co. LLC, DBA HealthFirst2200
Naloxone HCl51662-1586-03HF Acquisition Co. LLC, DBA HealthFirst10 × 22,000
Naloxone HCl51662-1673-01Henry Schein Inc.10400
Naloxone HCl55150-0328-10Eugia US LLC10 × 104,000
Naloxone HCl55150-0345-10Eugia US LLC10 × 22,000
Naloxone HCl67457-0292-02Mylan Institutional LLC10 × 1400
Naloxone HCl67457-0299-10Mylan Institutional LLC10 × 104,000
Naloxone HCl67457-0599-02Mylan Institutional LLC10 × 1400
Naloxone HCl67457-0645-02Mylan Institutional LLC10 × 1400
Naloxone HCl67457-0987-10Mylan Institutional LLC10 × 104,000
Naloxone HCl67457-0992-02Mylan Institutional LLC2400
Naloxone HCl70069-0071-10Somerset Pharma, LLC10 × 1400
Naloxone HCl70069-0072-10Somerset Pharma, LLC10 × 104,000
Naloxone HCl70756-0658-10Lifestar Pharma10 × 1400
Naloxone HCl70756-0658-25Lifestar Pharma25 × 11,000
Naloxone HCl70756-0850-10Lifestar Pharma10 × 1400
Naloxone HCl72572-0450-25Civica, Inc.25 × 11,000
Naloxone HCl72603-0590-10Northstar RxLLC10 × 1400
Naloxone HCl72603-0590-25Northstar RxLLC25 × 11,000
Naloxone HCl76045-0112-20FreseniUS Kabi USA, LLC24 × 24,800
Naloxone HCl76045-0114-10FreseniUS Kabi USA, LLC24 × 1960

J2312: common questions

Is J2312 a CPT code?
No. J2312 is a HCPCS Level II code, maintained by CMS, that identifies a drug with no specific code of its own. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDC goes with J2312?
None is fixed. J2312 is used for drugs that have no specific HCPCS code, so the claim carries the NDC of the drug actually given and its quantity, and payers usually also ask for the drug name and dose. How to find a J-code.
What is the Medicare payment limit for J2312?
$0.076 per 0.01 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

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