In short

Nypozi is billed under HCPCS Q5148 — Injection, filgrastim-txid (nypozi), biosimilar, 1 microgram. One billing unit is 1 mcg. CMS's crosswalk lists 8 Nypozi NDCs under this code.

Q5148 code details

Reference

Q5148
Injection, filgrastim-txid (nypozi), biosimilar, 1 microgramBilling unit: 1 mcg
Labelers
Cipla USA, Inc.; Tanvex BioPharma USA, Inc.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$1.026
Per1 mcg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Nypozi units and claim line

Enter the dose given to get the Q5148 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Nypozi NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Nypozi NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
69097-0429-67Q5148Cipla USA, Inc.0.8480
69097-0429-96Q5148Cipla USA, Inc.10 × 0.84800
69097-0430-67Q5148Cipla USA, Inc.0.5300
69097-0430-96Q5148Cipla USA, Inc.10 × 0.53000
72374-0101-01Q5148Tanvex BioPharma USA, Inc.0.5300
72374-0101-10Q5148Tanvex BioPharma USA, Inc.10 × 0.53000
72374-0102-01Q5148Tanvex BioPharma USA, Inc.0.8480
72374-0102-10Q5148Tanvex BioPharma USA, Inc.10 × 0.84800

Nypozi: common questions

What is the HCPCS code for Nypozi?
Nypozi is billed under HCPCS Q5148 — Injection, filgrastim-txid (nypozi), biosimilar, 1 microgram. One billing unit is 1 mcg. CMS's crosswalk lists 8 Nypozi NDCs under this code.
How many Q5148 billing units are in a package of Nypozi?
CMS lists 300 to 4,800 billing units per package, depending on the NDC, where one unit is 1 mcg. Units to report are based on the dose given, not the package.
Is Q5148 a CPT code?
No. Q5148 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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