In short

Q5148 is the HCPCS Level II code for injection, filgrastim-txid (nypozi), biosimilar, 1 microgram. CMS assigns NDCs for Nypozi to it. One billing unit is 1 microgram. The Medicare Part B payment limit is $1.026 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file
HCPCS codeQ5148
Billing unit1 microgram
Descriptor
Injection, filgrastim-txid (nypozi), biosimilar, 1 microgram
Short descriptor
Inj, nyposi 1 mcg
Code set
HCPCS Level II, maintained by CMS
Effective
Apr 1, 2025

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$1.026
Per1 mcg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Enter the units to build the claim line.

NDCs billed under Q5148

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 8 NDCs to Q5148 for Nypozi. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to Q5148 in the CMS ASP crosswalk
DrugNDC (11-digit)LabelerPackageBilling units per package
Nypozi69097-0429-67Cipla USA, Inc.0.8480
Nypozi69097-0429-96Cipla USA, Inc.10 × 0.84,800
Nypozi69097-0430-67Cipla USA, Inc.0.5300
Nypozi69097-0430-96Cipla USA, Inc.10 × 0.53,000
Nypozi72374-0101-01Tanvex BioPharma USA, Inc.0.5300
Nypozi72374-0101-10Tanvex BioPharma USA, Inc.10 × 0.53,000
Nypozi72374-0102-01Tanvex BioPharma USA, Inc.0.8480
Nypozi72374-0102-10Tanvex BioPharma USA, Inc.10 × 0.84,800

Q5148: common questions

Is Q5148 a CPT code?
No. Q5148 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under Q5148?
CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 8 NDCs under Q5148, for Nypozi. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for Q5148?
$1.026 per 1 mcg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
What is one billing unit of Q5148?
One unit of Q5148 is 1 microgram, as stated in the code's descriptor. Units to report = dose given ÷ 1 microgram. J-code billing units.

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