In short

CMS assigns Ondansetron HCl NDCs to 2 HCPCS codes: J2405 (per 1 mg), Q0162 (per 1 mg). Which one applies depends on the product; the table lists each NDC with its code.

J2405 code detailsQ0162 code details

Reference

J2405
Injection, ondansetron hydrochloride, per 1 mgBilling unit: 1 mg
Q0162
Ondansetron 1 mg, oral, fda approved prescription anti-emetic, for use as a complete therapeutic substitute for an iv anti-emetic at the time of chemotherapy treatment, not to exceed a 48 hour dosage regimenBilling unit: 1 mg
Labelers
A-S Medication Solutions; Accord Healthcare Inc; American Health Packaging; Apotex Corp; Athenex Pharmaceutical Division, LLC; AvPAK; Baxter Healthcare Corporation; Chartwelland 15 more

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.084
Per1 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.016
Per1 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Ondansetron HCl units and claim line

Enter the dose given to get the J2405 units and the NDC line for the CMS-1500 and the 837P. This builds the J2405 line; use the code page for Q0162.

Enter the dose given to build the claim line.

Ondansetron HCl NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Ondansetron HCl NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00404-9930-02J2405Henry Schein Inc.24
00409-0009-25J2405Pfizer Inc25 × 2100
00409-2271-25J2405Pfizer Inc25 × 2100
00409-4755-03J2405Pfizer Inc25 × 2100
00409-4759-01J2405Pfizer Inc2040
00641-6078-25J2405Hikma Pharmaceuticals USA Inc.25 × 2100
00641-6079-01J2405Hikma Pharmaceuticals USA Inc.2040
00641-6080-25J2405Hikma Pharmaceuticals USA Inc.25 × 2100
00641-6286-01J2405Hikma Pharmaceuticals USA Inc.2040
16729-0298-05J2405Accord Healthcare Inc2040
23155-0547-42J2405Heritage Pharmaceuticals Inc.25 × 2100
23155-0548-42J2405Heritage Pharmaceuticals Inc.25 × 2100
23155-0549-31J2405Heritage Pharmaceuticals Inc.2040
23155-0550-31J2405Heritage Pharmaceuticals Inc.2040
25021-0777-02J2405Sagent Pharmaceuticals25 × 2100
36000-0012-25J2405Baxter Healthcare Corporation25 × 2100
51662-1245-01J2405HF Acquisition Co. LLC, DBA HealthFirst24
51662-1245-03J2405HF Acquisition Co. LLC, DBA HealthFirst25 × 2100
51662-1377-01J2405HF Acquisition Co. LLC, DBA HealthFirst2040
60505-6130-05J2405Apotex Corp25 × 2100
63323-0373-02J2405FreseniUS Kabi USA, LLC25 × 2100
63323-0374-20J2405FreseniUS Kabi USA, LLC2040
65219-0323-02J2405FreseniUS Kabi USA, LLC25 × 2100
70860-0776-02J2405Athenex Pharmaceutical Division, LLC25 × 2100
70860-0777-21J2405Athenex Pharmaceutical Division, LLC10 × 20400
72266-0123-25J2405Fosun Pharma USA Inc.25 × 2100
72266-0124-01J2405Fosun Pharma USA Inc.2040
72572-0520-25J2405Civica, Inc.25 × 2100
76045-0216-20J2405FreseniUS Kabi USA, LLC24 × 296
00904-6551-61Q0162Major Pharmaceuticals100400
00904-6552-61Q0162Major Pharmaceuticals100800
16714-0159-01Q0162Northstar RxLLC30120
16714-0160-01Q0162Northstar RxLLC30240
43063-0792-06Q0162PD-Rx Pharmaceuticals, Inc.648
50090-3178-00Q0162A-S Medication Solutions1040
50090-3178-01Q0162A-S Medication Solutions624
50090-3178-02Q0162A-S Medication Solutions2080
50090-3178-04Q0162A-S Medication Solutions312
50090-3178-05Q0162A-S Medication Solutions1248
50090-3185-00Q0162A-S Medication Solutions432
50090-6342-00Q0162A-S Medication Solutions1040
50090-6342-01Q0162A-S Medication Solutions624
50090-6342-02Q0162A-S Medication Solutions2080
50090-6342-05Q0162A-S Medication Solutions1248
50268-0621-15Q0162AvPAK50200
50268-0622-15Q0162AvPAK50400
50268-0647-14Q0162AvPAK40 × 5160
55111-0153-30Q0162Dr. Reddy's Laboratories Inc.30120
55111-0154-30Q0162Dr. Reddy's Laboratories Inc.30240
60687-0252-86Q0162American Health Packaging30 × 5120
62135-0350-30Q0162Chartwell30120
62135-0351-05Q0162Chartwell5004000
62135-0351-30Q0162Chartwell30240
62135-0555-24Q0162Chartwell20 × 580
62135-0555-58Q0162Chartwell5040
68084-0220-01Q0162American Health Packaging100400
68084-0221-01Q0162American Health Packaging100800
68462-0105-30Q0162Glenmark Pharmaceuticals Inc., USA30120
68462-0106-30Q0162Glenmark Pharmaceuticals Inc., USA30240
68788-8582-02Q0162Preferred Pharmaceuticals Inc1296
68788-8582-03Q0162Preferred Pharmaceuticals Inc30240
68788-8651-01Q0162Preferred Pharmaceuticals Inc1040
68788-8651-03Q0162Preferred Pharmaceuticals Inc30120
68788-8651-05Q0162Preferred Pharmaceuticals Inc1560
68788-9368-01Q0162Preferred Pharmaceuticals Inc1040
68788-9368-02Q0162Preferred Pharmaceuticals Inc1248
68788-9402-01Q0162Preferred Pharmaceuticals Inc1080
72789-0034-12Q0162PD-Rx Pharmaceuticals, Inc.30120

Ondansetron HCl: common questions

What is the HCPCS code for Ondansetron HCl?
CMS assigns Ondansetron HCl NDCs to 2 HCPCS codes: J2405 (per 1 mg), Q0162 (per 1 mg). Which one applies depends on the product; the table lists each NDC with its code.
How many J2405 billing units are in a package of Ondansetron HCl?
CMS lists 4 to 400 billing units per package, depending on the NDC, where one unit is 1 mg. Units to report are based on the dose given, not the package.
How many Q0162 billing units are in a package of Ondansetron HCl?
CMS lists 12 to 4,000 billing units per package, depending on the NDC, where one unit is 1 mg. Units to report are based on the dose given, not the package.
Is J2405 a CPT code?
No. J2405 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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