No. J2405 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code.

What NDCs are billed under J2405?

CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 29 NDCs under J2405, for Ondansetron HCl. The table on this page shows each one with its billing units per package.

What is the Medicare payment limit for J2405?

$0.084 per 1 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

What is one billing unit of J2405?

One unit of J2405 is 1 mg, as stated in the code's descriptor. Units to report = dose given ÷ 1 mg.

J2405 J-Code: Ondansetron hydrochloride

In short

J2405 is the HCPCS Level II code for injection, ondansetron hydrochloride, per 1 mg. CMS assigns NDCs for Ondansetron HCl to it. One billing unit is 1 mg. The Medicare Part B payment limit is $0.084 per unit (October 1, 2026 through December 31, 2026).

Code

Med-Code curated

HCPCS codeJ2405

Billing unit1 mg

Descriptor: Injection, ondansetron hydrochloride, per 1 mg
Code set: HCPCS Level II, maintained by CMS
Category: Antiemetic / 5-HT3

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$0.084

Per1 mg

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Units = dose given ÷ 1 mg. For example, 100 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Dose given (mg)

HCPCS units (1 unit = 1 mg)

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the dose given to build the claim line.

Drugs mapped to J2405

FDA-listed products billed under J2405

Finished products in the FDA NDC Directory whose brand or single active ingredient, and route, match this code’s entry.

NDC products matching J2405
Product	Strength	Form · route	Labeler	Product NDC
Ondansetron	Ondansetron hydrochloride 2 mg/mL	InjectionIntramuscular, Intravenous	HF Acquisition Co LLC, DBA HealthFirst	51662-1245
Ondansetron	Ondansetron hydrochloride 2 mg/mL	Injection, SolutionIntramuscular, Intravenous	Medical Purchasing Solutions, LLC	71872-7162
Ondansetron	Ondansetron hydrochloride 2 mg/mL	InjectionIntramuscular, Intravenous	A-S Medication Solutions	50090-4935
Ondansetronondansetron hydrochloride	Ondansetron hydrochloride 2 mg/mL	InjectionIntramuscular, Intravenous	Fresenius Kabi USA, LLC	63323-373
Ondansetronondansetron hydrochloride	Ondansetron hydrochloride 2 mg/mL	InjectionIntramuscular, Intravenous	Fresenius Kabi USA, LLC	63323-374
Ondansetronondansetron hydrochloride	Ondansetron hydrochloride 2 mg/mL	InjectionIntramuscular, Intravenous	Fresenius Kabi USA, LLC	65219-323

All NDCs for these drugs

NDCs billed under J2405

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 29 NDCs to J2405 for Ondansetron HCl. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J2405 in the CMS ASP crosswalk
Drug	NDC (11-digit)	Labeler	Package	Billing units per package
Ondansetron HCl	00404-9930-02	Henry Schein Inc.	2	4
Ondansetron HCl	00409-0009-25	Pfizer Inc	25 × 2	100
Ondansetron HCl	00409-2271-25	Pfizer Inc	25 × 2	100
Ondansetron HCl	00409-4755-03	Pfizer Inc	25 × 2	100
Ondansetron HCl	00409-4759-01	Pfizer Inc	20	40
Ondansetron HCl	00641-6078-25	Hikma Pharmaceuticals USA Inc.	25 × 2	100
Ondansetron HCl	00641-6079-01	Hikma Pharmaceuticals USA Inc.	20	40
Ondansetron HCl	00641-6080-25	Hikma Pharmaceuticals USA Inc.	25 × 2	100
Ondansetron HCl	00641-6286-01	Hikma Pharmaceuticals USA Inc.	20	40
Ondansetron HCl	16729-0298-05	Accord Healthcare Inc	20	40
Ondansetron HCl	23155-0547-42	Heritage Pharmaceuticals Inc.	25 × 2	100
Ondansetron HCl	23155-0548-42	Heritage Pharmaceuticals Inc.	25 × 2	100
Ondansetron HCl	23155-0549-31	Heritage Pharmaceuticals Inc.	20	40
Ondansetron HCl	23155-0550-31	Heritage Pharmaceuticals Inc.	20	40
Ondansetron HCl	25021-0777-02	Sagent Pharmaceuticals	25 × 2	100
Ondansetron HCl	36000-0012-25	Baxter Healthcare Corporation	25 × 2	100
Ondansetron HCl	51662-1245-01	HF Acquisition Co. LLC, DBA HealthFirst	2	4
Ondansetron HCl	51662-1245-03	HF Acquisition Co. LLC, DBA HealthFirst	25 × 2	100
Ondansetron HCl	51662-1377-01	HF Acquisition Co. LLC, DBA HealthFirst	20	40
Ondansetron HCl	60505-6130-05	Apotex Corp	25 × 2	100
Ondansetron HCl	63323-0373-02	FreseniUS Kabi USA, LLC	25 × 2	100
Ondansetron HCl	63323-0374-20	FreseniUS Kabi USA, LLC	20	40
Ondansetron HCl	65219-0323-02	FreseniUS Kabi USA, LLC	25 × 2	100
Ondansetron HCl	70860-0776-02	Athenex Pharmaceutical Division, LLC	25 × 2	100
Ondansetron HCl	70860-0777-21	Athenex Pharmaceutical Division, LLC	10 × 20	400
Ondansetron HCl	72266-0123-25	Fosun Pharma USA Inc.	25 × 2	100
Ondansetron HCl	72266-0124-01	Fosun Pharma USA Inc.	20	40
Ondansetron HCl	72572-0520-25	Civica, Inc.	25 × 2	100
Ondansetron HCl	76045-0216-20	FreseniUS Kabi USA, LLC	24 × 2	96

J2405: common questions

Is J2405 a CPT code?: No. J2405 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J2405?: CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 29 NDCs under J2405, for Ondansetron HCl. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J2405?: $0.084 per 1 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
What is one billing unit of J2405?: One unit of J2405 is 1 mg, as stated in the code's descriptor. Units to report = dose given ÷ 1 mg. J-code billing units.

J2405 — Injection, ondansetron hydrochloride, per 1 mg