In short

Palonosetron Hydrochloride is billed under HCPCS J2469 — Injection, palonosetron hcl, 25 mcg. One billing unit is 25 mcg. CMS's crosswalk lists 1 Palonosetron Hydrochloride NDC under this code.

J2469 code details

Reference

J2469
Injection, palonosetron hcl, 25 mcgBilling unit: 25 mcg
Labelers
Apotex Corp

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.469
Per25 mcg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: AMP-based payment limit. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Palonosetron Hydrochloride units and claim line

Enter the dose given to get the J2469 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Palonosetron Hydrochloride NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Palonosetron Hydrochloride NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
60505-6439-01J2469Apotex Corp510

Palonosetron Hydrochloride: common questions

What is the J-code for Palonosetron Hydrochloride?
Palonosetron Hydrochloride is billed under HCPCS J2469 — Injection, palonosetron hcl, 25 mcg. One billing unit is 25 mcg. CMS's crosswalk lists 1 Palonosetron Hydrochloride NDC under this code.
How many J2469 billing units are in a package of Palonosetron Hydrochloride?
CMS lists 10 billing units per package, depending on the NDC, where one unit is 25 mcg. Units to report are based on the dose given, not the package.
Is J2469 a CPT code?
No. J2469 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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