HCPCS Level II drug code
J2469 — Injection, palonosetron hcl, 25 mcg
In short
J2469 is the HCPCS Level II code for injection, palonosetron hcl, 25 mcg. CMS assigns NDCs for Palonosetron, Palonosetron HCl and Palonosetron Hydrochloride to it. One billing unit is 25 mcg. The Medicare Part B payment limit is $0.469 per unit (October 1, 2026 through December 31, 2026).
Code
CMS HCPCS file- Descriptor
- Injection, palonosetron hcl, 25 mcg
- Short descriptor
- Palonosetron hcl
- Code set
- HCPCS Level II, maintained by CMS
- Effective
- Jan 1, 2024
The billing unit is read from the descriptor. Confirm it against the CMS file before billing.
Medicare Part B payment limit
CMS ASP fileEffective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: AMP-based payment limit. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files
Units and claim line
Units = dose given ÷ 25 mcg. For example, 2500 mcg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.
Enter the dose given to build the claim line.
NDCs billed under J2469
CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 22 NDCs to J2469 for Palonosetron, Palonosetron HCl and Palonosetron Hydrochloride. Billing units per package are CMS’s figures for this code’s unit.
| Drug | NDC (11-digit) | Labeler | Package | Billing units per package |
|---|---|---|---|---|
| Palonosetron | 00409-2504-10 | Pfizer Inc | 5 | 10 |
| Palonosetron | 00703-4094-01 | Teva Parenteral Medicines, Inc. | 5 | 10 |
| Palonosetron | 00781-3312-75 | Sandoz Inc. | 5 | 10 |
| Palonosetron | 00781-3312-95 | Sandoz Inc. | 10 × 5 | 100 |
| Palonosetron | 00781-3415-75 | Sandoz Inc. | 5 | 10 |
| Palonosetron | 16714-0834-01 | Northstar RxLLC | 5 | 10 |
| Palonosetron | 25021-0783-05 | Sagent Pharmaceuticals | 5 | 10 |
| Palonosetron | 25021-0788-74 | Sagent Pharmaceuticals | 5 × 5 | 50 |
| Palonosetron | 36000-0326-02 | Baxter Healthcare Corporation | 5 | 10 |
| Palonosetron | 55111-0694-07 | Dr. Reddy's Laboratories Inc. | 5 | 10 |
| Palonosetron | 55150-0186-05 | Eugia US LLC | 5 | 10 |
| Palonosetron | 60505-6193-01 | Apotex Corp | 5 | 10 |
| Palonosetron | 63323-0673-05 | FreseniUS Kabi USA, LLC | 5 | 10 |
| Palonosetron | 63323-0673-89 | FreseniUS Kabi USA, LLC | 10 × 5 | 100 |
| Palonosetron | 67457-0317-25 | Mylan Institutional LLC | 5 | 10 |
| Palonosetron | 68001-0355-25 | BluePoint Laboratories | 5 | 10 |
| Palonosetron | 69543-0371-10 | Virtus Pharmaceuticals, LLC | 10 × 5 | 100 |
| Palonosetron | 71288-0409-05 | Meitheal Pharmaceuticals Inc. | 5 | 10 |
| Palonosetron HCl | 00781-3415-95 | Sandoz Inc. | 10 × 5 | 100 |
| Palonosetron HCl | 60505-6193-04 | Apotex Corp | 10 × 5 | 100 |
| Palonosetron HCl | 83634-0777-05 | Avenacy Inc. | 5 | 10 |
| Palonosetron Hydrochloride | 60505-6439-01 | Apotex Corp | 5 | 10 |
J2469: common questions
- Is J2469 a CPT code?
- No. J2469 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
- What NDCs are billed under J2469?
- CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 22 NDCs under J2469, for Palonosetron, Palonosetron HCl and Palonosetron Hydrochloride. The table on this page shows each one with its billing units per package.
- What is the Medicare payment limit for J2469?
- $0.469 per 25 mcg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
- What is one billing unit of J2469?
- One unit of J2469 is 25 mcg, as stated in the code's descriptor. Units to report = dose given ÷ 25 mcg. J-code billing units.