In short

Palonosetron is billed under HCPCS J2469 — Injection, palonosetron hcl, 25 mcg. One billing unit is 25 mcg. CMS's crosswalk lists 18 Palonosetron NDCs under this code.

J2469 code details

Reference

J2469
Injection, palonosetron hcl, 25 mcgBilling unit: 25 mcg
Labelers
Apotex Corp; Baxter Healthcare Corporation; BluePoint Laboratories; Dr. Reddy's Laboratories Inc.; Eugia US LLC; FreseniUS Kabi USA, LLC; Meitheal Pharmaceuticals Inc.; Mylan Institutional LLCand 6 more

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.469
Per25 mcg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: AMP-based payment limit. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Palonosetron units and claim line

Enter the dose given to get the J2469 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Palonosetron NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Palonosetron NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00409-2504-10J2469Pfizer Inc510
00703-4094-01J2469Teva Parenteral Medicines, Inc.510
00781-3312-75J2469Sandoz Inc.510
00781-3312-95J2469Sandoz Inc.10 × 5100
00781-3415-75J2469Sandoz Inc.510
16714-0834-01J2469Northstar RxLLC510
25021-0783-05J2469Sagent Pharmaceuticals510
25021-0788-74J2469Sagent Pharmaceuticals5 × 550
36000-0326-02J2469Baxter Healthcare Corporation510
55111-0694-07J2469Dr. Reddy's Laboratories Inc.510
55150-0186-05J2469Eugia US LLC510
60505-6193-01J2469Apotex Corp510
63323-0673-05J2469FreseniUS Kabi USA, LLC510
63323-0673-89J2469FreseniUS Kabi USA, LLC10 × 5100
67457-0317-25J2469Mylan Institutional LLC510
68001-0355-25J2469BluePoint Laboratories510
69543-0371-10J2469Virtus Pharmaceuticals, LLC10 × 5100
71288-0409-05J2469Meitheal Pharmaceuticals Inc.510

Palonosetron: common questions

What is the J-code for Palonosetron?
Palonosetron is billed under HCPCS J2469 — Injection, palonosetron hcl, 25 mcg. One billing unit is 25 mcg. CMS's crosswalk lists 18 Palonosetron NDCs under this code.
How many J2469 billing units are in a package of Palonosetron?
CMS lists 10 to 100 billing units per package, depending on the NDC, where one unit is 25 mcg. Units to report are based on the dose given, not the package.
Is J2469 a CPT code?
No. J2469 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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