In short

Papzimeos is billed under HCPCS J3404 — Injection, zopapogene imadenovec-drba suspension, per therapeutic dose. One billing unit is per therapeutic dose. CMS's crosswalk lists 1 Papzimeos NDC under this code.

J3404 code details

Reference

J3404
Injection, zopapogene imadenovec-drba suspension, per therapeutic doseBilling unit: per therapeutic dose
Labelers
Precigen, Inc.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$119,675.512
Perper therapeutic dose
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: Added October 2026. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Papzimeos units and claim line

Enter the dose given to get the J3404 units and the NDC line for the CMS-1500 and the 837P.

Enter the units to build the claim line.

Papzimeos NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Papzimeos NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
84768-0511-01J3404Precigen, Inc.11

Papzimeos: common questions

What is the J-code for Papzimeos?
Papzimeos is billed under HCPCS J3404 — Injection, zopapogene imadenovec-drba suspension, per therapeutic dose. One billing unit is per therapeutic dose. CMS's crosswalk lists 1 Papzimeos NDC under this code.
How many J3404 billing units are in a package of Papzimeos?
CMS lists 1 billing units per package, depending on the NDC, where one unit is per therapeutic dose. Units to report are based on the dose given, not the package.
Is J3404 a CPT code?
No. J3404 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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