No. J3404 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code.

What NDCs are billed under J3404?

CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 1 NDC under J3404, for Papzimeos. The table on this page shows each one with its billing units per package.

What is the Medicare payment limit for J3404?

$119,675.512 per per therapeutic dose, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

J3404 J-Code: Papzimeos

In short

J3404 is the HCPCS Level II code for injection, zopapogene imadenovec-drba suspension, per therapeutic dose. CMS assigns NDCs for Papzimeos to it. The Medicare Part B payment limit is $119,675.512 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file

HCPCS codeJ3404

Billing unitSee descriptor

Descriptor: Injection, zopapogene imadenovec-drba suspension, per therapeutic dose
Short descriptor: Inj zopapogene per ther dose
Code set: HCPCS Level II, maintained by CMS
Effective: Apr 1, 2026

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$119,675.512

Perper therapeutic dose

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: Added October 2026. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

HCPCS units

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the units to build the claim line.

NDCs billed under J3404

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 1 NDC to J3404 for Papzimeos. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J3404 in the CMS ASP crosswalk
Drug	NDC (11-digit)	Labeler	Package	Billing units per package
Papzimeos	84768-0511-01	Precigen, Inc.	1	1

J3404: common questions

Is J3404 a CPT code?: No. J3404 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J3404?: CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 1 NDC under J3404, for Papzimeos. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J3404?: $119,675.512 per per therapeutic dose, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

J3404 — Injection, zopapogene imadenovec-drba suspension, per therapeutic dose