In short

Piperacillin And Tazobactam is billed under HCPCS J2543 — Injection, piperacillin sodium/tazobactam sodium, 1 gram/0.125 grams (1.125 grams). One billing unit is 1.125 gm. CMS's crosswalk lists 1 Piperacillin And Tazobactam NDC under this code.

J2543 code details

Reference

J2543
Injection, piperacillin sodium/tazobactam sodium, 1 gram/0.125 grams (1.125 grams)Billing unit: 1.125 gm
Labelers
Pfizer Inc

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$1.183
Per1.125 gm
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Piperacillin And Tazobactam units and claim line

Enter the dose given to get the J2543 units and the NDC line for the CMS-1500 and the 837P.

Enter the units to build the claim line.

Piperacillin And Tazobactam NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Piperacillin And Tazobactam NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00409-3390-10J2543Pfizer Inc10 × 140

Piperacillin And Tazobactam: common questions

What is the J-code for Piperacillin And Tazobactam?
Piperacillin And Tazobactam is billed under HCPCS J2543 — Injection, piperacillin sodium/tazobactam sodium, 1 gram/0.125 grams (1.125 grams). One billing unit is 1.125 gm. CMS's crosswalk lists 1 Piperacillin And Tazobactam NDC under this code.
How many J2543 billing units are in a package of Piperacillin And Tazobactam?
CMS lists 40 billing units per package, depending on the NDC, where one unit is 1.125 gm. Units to report are based on the dose given, not the package.
Is J2543 a CPT code?
No. J2543 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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