HCPCS drug code · CMS crosswalk
Promethazine HCl J-Code / HCPCS Code
In short
Promethazine HCl is billed under HCPCS J2550 — Injection, promethazine hcl, up to 50 mg. One billing unit is 50 mg. CMS's crosswalk lists 19 Promethazine HCl NDCs under this code.
Reference
- J2550
- Injection, promethazine hcl, up to 50 mgBilling unit: 50 mg
- Labelers
- A-S Medication Solutions; HF Acquisition Co. LLC, DBA HealthFirst; Henry Schein Inc.; Hikma Pharmaceuticals USA Inc.; XGen Pharmaceuticals DJB, Inc.
Medicare Part B payment limit
CMS ASP fileEffective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files
Promethazine HCl units and claim line
Enter the dose given to get the J2550 units and the NDC line for the CMS-1500 and the 837P.
Enter the dose given to build the claim line.
Promethazine HCl NDCs and billing units
From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.
| NDC (11-digit) | HCPCS | Labeler | Package | Billing units per package |
|---|---|---|---|---|
| 00404-9940-01 | J2550 | Henry Schein Inc. | 1 | 1 |
| 00404-9941-01 | J2550 | Henry Schein Inc. | 1 | 1 |
| 00404-9942-01 | J2550 | Henry Schein Inc. | 1 | 1 |
| 00641-0928-25 | J2550 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 13 |
| 00641-0929-25 | J2550 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 25 |
| 00641-0948-35 | J2550 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 13 |
| 00641-0949-35 | J2550 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 25 |
| 00641-0955-25 | J2550 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 13 |
| 00641-0956-25 | J2550 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 25 |
| 00641-1495-35 | J2550 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 13 |
| 00641-1496-35 | J2550 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 25 |
| 00641-6208-25 | J2550 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 13 |
| 39822-5525-03 | J2550 | XGen Pharmaceuticals DJB, Inc. | 25 × 1 | 13 |
| 39822-5550-06 | J2550 | XGen Pharmaceuticals DJB, Inc. | 25 × 1 | 25 |
| 50090-0879-00 | J2550 | A-S Medication Solutions | 25 × 1 | 25 |
| 51662-1247-01 | J2550 | HF Acquisition Co. LLC, DBA HealthFirst | 1 | 1 |
| 51662-1247-03 | J2550 | HF Acquisition Co. LLC, DBA HealthFirst | 25 × 1 | 13 |
| 51662-1248-01 | J2550 | HF Acquisition Co. LLC, DBA HealthFirst | 1 | 1 |
| 51662-1248-03 | J2550 | HF Acquisition Co. LLC, DBA HealthFirst | 25 × 1 | 25 |
Promethazine HCl: common questions
- What is the J-code for Promethazine HCl?
- Promethazine HCl is billed under HCPCS J2550 — Injection, promethazine hcl, up to 50 mg. One billing unit is 50 mg. CMS's crosswalk lists 19 Promethazine HCl NDCs under this code.
- How many J2550 billing units are in a package of Promethazine HCl?
- CMS lists 1 to 25 billing units per package, depending on the NDC, where one unit is 50 mg. Units to report are based on the dose given, not the package.
- Is J2550 a CPT code?
- No. J2550 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.