HCPCS Level II drug code
J2550 — Injection, promethazine hcl, up to 50 mg
In short
J2550 is the HCPCS Level II code for injection, promethazine hcl, up to 50 mg. CMS assigns NDCs for Phenergan and Promethazine HCl to it. The Medicare Part B payment limit is $3.241 per unit (October 1, 2026 through December 31, 2026).
Code
CMS HCPCS file- Descriptor
- Injection, promethazine hcl, up to 50 mg
- Short descriptor
- Promethazine hcl injection
- Code set
- HCPCS Level II, maintained by CMS
- Effective
- Jan 1, 1997
Medicare Part B payment limit
CMS ASP fileEffective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files
Units and claim line
Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.
Enter the units to build the claim line.
NDCs billed under J2550
CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 23 NDCs to J2550 for Phenergan and Promethazine HCl. Billing units per package are CMS’s figures for this code’s unit.
| Drug | NDC (11-digit) | Labeler | Package | Billing units per package |
|---|---|---|---|---|
| Phenergan | 00641-6082-25 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 13 |
| Phenergan | 00641-6083-25 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 25 |
| Phenergan | 00641-6084-25 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 13 |
| Phenergan | 00641-6085-25 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 25 |
| Promethazine HCl | 00404-9940-01 | Henry Schein Inc. | 1 | 1 |
| Promethazine HCl | 00404-9941-01 | Henry Schein Inc. | 1 | 1 |
| Promethazine HCl | 00404-9942-01 | Henry Schein Inc. | 1 | 1 |
| Promethazine HCl | 00641-0928-25 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 13 |
| Promethazine HCl | 00641-0929-25 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 25 |
| Promethazine HCl | 00641-0948-35 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 13 |
| Promethazine HCl | 00641-0949-35 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 25 |
| Promethazine HCl | 00641-0955-25 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 13 |
| Promethazine HCl | 00641-0956-25 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 25 |
| Promethazine HCl | 00641-1495-35 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 13 |
| Promethazine HCl | 00641-1496-35 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 25 |
| Promethazine HCl | 00641-6208-25 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 13 |
| Promethazine HCl | 39822-5525-03 | XGen Pharmaceuticals DJB, Inc. | 25 × 1 | 13 |
| Promethazine HCl | 39822-5550-06 | XGen Pharmaceuticals DJB, Inc. | 25 × 1 | 25 |
| Promethazine HCl | 50090-0879-00 | A-S Medication Solutions | 25 × 1 | 25 |
| Promethazine HCl | 51662-1247-01 | HF Acquisition Co. LLC, DBA HealthFirst | 1 | 1 |
| Promethazine HCl | 51662-1247-03 | HF Acquisition Co. LLC, DBA HealthFirst | 25 × 1 | 13 |
| Promethazine HCl | 51662-1248-01 | HF Acquisition Co. LLC, DBA HealthFirst | 1 | 1 |
| Promethazine HCl | 51662-1248-03 | HF Acquisition Co. LLC, DBA HealthFirst | 25 × 1 | 25 |
J2550: common questions
- Is J2550 a CPT code?
- No. J2550 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
- What NDCs are billed under J2550?
- CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 23 NDCs under J2550, for Phenergan and Promethazine HCl. The table on this page shows each one with its billing units per package.
- What is the Medicare payment limit for J2550?
- $3.241 per 50 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.