How many J7639 billing units are in a package of Pulmozyme?

CMS lists 75 billing units per package, depending on the NDC, where one unit is 1 mg. Units to report are based on the dose given, not the package.

No. J7639 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Pulmozyme J-Code J7639 — Billing Units & NDCs

In short

Pulmozyme is billed under HCPCS J7639 — Dornase alfa, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose form, per milligram. One billing unit is 1 mg. CMS's crosswalk lists 1 Pulmozyme NDC under this code.

J7639 code details

Reference

J7639: Dornase alfa, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose form, per milligramBilling unit: 1 mg
Labelers: Genentech, Inc.

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$56.806

Per1 mg

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Pulmozyme units and claim line

Enter the dose given to get the J7639 units and the NDC line for the CMS-1500 and the 837P.

Dose given (mg)

HCPCS units (1 unit = 1 mg)

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the dose given to build the claim line.

Pulmozyme NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Pulmozyme NDCs in the CMS ASP crosswalk
NDC (11-digit)	HCPCS	Labeler	Package	Billing units per package
50242-0100-40	J7639	Genentech, Inc.	30 × 2.5	75

Pulmozyme: common questions

What is the J-code for Pulmozyme?: Pulmozyme is billed under HCPCS J7639 — Dornase alfa, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose form, per milligram. One billing unit is 1 mg. CMS's crosswalk lists 1 Pulmozyme NDC under this code.
How many J7639 billing units are in a package of Pulmozyme?: CMS lists 75 billing units per package, depending on the NDC, where one unit is 1 mg. Units to report are based on the dose given, not the package.
Is J7639 a CPT code?: No. J7639 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Pulmozyme J-Code / HCPCS Code