In short

J7639 is the HCPCS Level II code for dornase alfa, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose form, per milligram. CMS assigns NDCs for Pulmozyme to it. The Medicare Part B payment limit is $56.806 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file
HCPCS codeJ7639
Billing unitSee descriptor
Descriptor
Dornase alfa, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose form, per milligram
Short descriptor
Dornase alfa non-comp unit
Code set
HCPCS Level II, maintained by CMS
Effective
Jan 1, 2009

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$56.806
Per1 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Enter the units to build the claim line.

NDCs billed under J7639

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 1 NDC to J7639 for Pulmozyme. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J7639 in the CMS ASP crosswalk
DrugNDC (11-digit)LabelerPackageBilling units per package
Pulmozyme50242-0100-40Genentech, Inc.30 × 2.575

J7639: common questions

Is J7639 a CPT code?
No. J7639 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J7639?
CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 1 NDC under J7639, for Pulmozyme. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J7639?
$56.806 per 1 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

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