In short

Releuko is billed under HCPCS Q5125 — Injection, filgrastim-ayow, biosimilar, (releuko), 1 microgram. One billing unit is 1 mcg. CMS's crosswalk lists 4 Releuko NDCs under this code.

Q5125 code details

Reference

Q5125
Injection, filgrastim-ayow, biosimilar, (releuko), 1 microgramBilling unit: 1 mcg
Labelers
Amneal Pharmaceuticals, LLC

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.308
Per1 mcg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: 8% of reference add-on applied. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Releuko units and claim line

Enter the dose given to get the Q5125 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Releuko NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Releuko NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
70121-1568-01Q5125Amneal Pharmaceuticals, LLC0.5300
70121-1568-07Q5125Amneal Pharmaceuticals, LLC10 × 0.53000
70121-1570-01Q5125Amneal Pharmaceuticals, LLC0.8480
70121-1570-07Q5125Amneal Pharmaceuticals, LLC10 × 0.84800

Releuko: common questions

What is the HCPCS code for Releuko?
Releuko is billed under HCPCS Q5125 — Injection, filgrastim-ayow, biosimilar, (releuko), 1 microgram. One billing unit is 1 mcg. CMS's crosswalk lists 4 Releuko NDCs under this code.
How many Q5125 billing units are in a package of Releuko?
CMS lists 300 to 4,800 billing units per package, depending on the NDC, where one unit is 1 mcg. Units to report are based on the dose given, not the package.
Is Q5125 a CPT code?
No. Q5125 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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