In short

Unasyn is billed under HCPCS J0295 — Injection, ampicillin sodium/sulbactam sodium, per 1.5 gm. One billing unit is 1.5 gm. CMS's crosswalk lists 3 Unasyn NDCs under this code.

J0295 code details

Reference

J0295
Injection, ampicillin sodium/sulbactam sodium, per 1.5 gmBilling unit: 1.5 gm
Labelers
Pfizer Inc

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$1.457
Per1.5 gm
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Unasyn units and claim line

Enter the dose given to get the J0295 units and the NDC line for the CMS-1500 and the 837P.

Enter the units to build the claim line.

Unasyn NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Unasyn NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00049-0013-83J0295Pfizer Inc10 × 110
00049-0014-83J0295Pfizer Inc10 × 120
00049-0024-28J0295Pfizer Inc110

Unasyn: common questions

What is the J-code for Unasyn?
Unasyn is billed under HCPCS J0295 — Injection, ampicillin sodium/sulbactam sodium, per 1.5 gm. One billing unit is 1.5 gm. CMS's crosswalk lists 3 Unasyn NDCs under this code.
How many J0295 billing units are in a package of Unasyn?
CMS lists 10 to 20 billing units per package, depending on the NDC, where one unit is 1.5 gm. Units to report are based on the dose given, not the package.
Is J0295 a CPT code?
No. J0295 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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