In short

Xeloda is billed under HCPCS J8522 — Capecitabine, oral, 50 mg. One billing unit is 50 mg. CMS's crosswalk lists 2 Xeloda NDCs under this code.

J8522 code details

Reference

J8522
Capecitabine, oral, 50 mgBilling unit: 50 mg
Labelers
Genentech, Inc.; H2 Pharma LLC

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.029
Per50 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Xeloda units and claim line

Enter the dose given to get the J8522 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Xeloda NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Xeloda NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00004-1100-20J8522Genentech, Inc.60180
61269-0470-60J8522H2 Pharma LLC60180

Xeloda: common questions

What is the J-code for Xeloda?
Xeloda is billed under HCPCS J8522 — Capecitabine, oral, 50 mg. One billing unit is 50 mg. CMS's crosswalk lists 2 Xeloda NDCs under this code.
How many J8522 billing units are in a package of Xeloda?
CMS lists 180 billing units per package, depending on the NDC, where one unit is 50 mg. Units to report are based on the dose given, not the package.
Is J8522 a CPT code?
No. J8522 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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