No. J8522 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code.

What NDCs are billed under J8522?

CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 25 NDCs under J8522, for Capecitabine and Xeloda. The table on this page shows each one with its billing units per package.

What is the Medicare payment limit for J8522?

$0.029 per 50 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

What is one billing unit of J8522?

One unit of J8522 is 50 mg, as stated in the code's descriptor. Units to report = dose given ÷ 50 mg.

J8522 J-Code: Xeloda (capecitabine) — Billing Units & NDCs

In short

J8522 is the HCPCS Level II code for capecitabine, oral, 50 mg. CMS assigns NDCs for Capecitabine and Xeloda to it. One billing unit is 50 mg. The Medicare Part B payment limit is $0.029 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file

HCPCS codeJ8522

Billing unit50 mg

Descriptor: Capecitabine, oral, 50 mg
Short descriptor: Capecitabine, oral, 50 mg
Code set: HCPCS Level II, maintained by CMS
Effective: Jan 1, 2025

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$0.029

Per50 mg

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Units = dose given ÷ 50 mg. For example, 5000 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Dose given (mg)

HCPCS units (1 unit = 50 mg)

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the dose given to build the claim line.

NDCs billed under J8522

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 25 NDCs to J8522 for Capecitabine and Xeloda. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J8522 in the CMS ASP crosswalk
Drug	NDC (11-digit)	Labeler	Package	Billing units per package
Capecitabine	00004-1101-50	Genentech, Inc.	120	1,200
Capecitabine	00093-7473-06	Teva Pharmaceuticals USA, Inc.	60	180
Capecitabine	00093-7474-89	Teva Pharmaceuticals USA, Inc.	120	1,200
Capecitabine	16729-0072-12	Accord Healthcare Inc	60	180
Capecitabine	16729-0073-29	Accord Healthcare Inc	120	1,200
Capecitabine	55111-0496-60	Dr. Reddy's Laboratories Inc.	60	180
Capecitabine	55111-0497-04	Dr. Reddy's Laboratories Inc.	120	1,200
Capecitabine	59651-0204-60	Aurobindo Pharma Usa, Inc.	60	180
Capecitabine	59651-0205-08	Aurobindo Pharma Usa, Inc.	120	1,200
Capecitabine	60687-0149-94	American Health Packaging	20	200
Capecitabine	67877-0458-60	Ascend Laboratories, LLC	60	180
Capecitabine	67877-0459-12	Ascend Laboratories, LLC	120	1,200
Capecitabine	68001-0487-06	BluePoint Laboratories	60	180
Capecitabine	68001-0488-07	BluePoint Laboratories	120	1,200
Capecitabine	68001-0643-06	BluePoint Laboratories	60	180
Capecitabine	68001-0644-07	BluePoint Laboratories	120	1,200
Capecitabine	69097-0948-08	Cipla USA, Inc.	120	1,200
Capecitabine	69097-0949-03	Cipla USA, Inc.	60	180
Capecitabine	70756-0815-60	Lifestar Pharma	60	180
Capecitabine	70756-0816-22	Lifestar Pharma	120	1,200
Capecitabine	72205-0006-60	Novadoz Pharmaceuticals LLC	60	180
Capecitabine	72205-0007-92	Novadoz Pharmaceuticals LLC	120	1,200
Capecitabine	82009-0112-12	Quallent Pharmaceuticals	120	1,200
Xeloda	00004-1100-20	Genentech, Inc.	60	180
Xeloda	61269-0470-60	H2 Pharma LLC	60	180

J8522: common questions

Is J8522 a CPT code?: No. J8522 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J8522?: CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 25 NDCs under J8522, for Capecitabine and Xeloda. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J8522?: $0.029 per 50 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
What is one billing unit of J8522?: One unit of J8522 is 50 mg, as stated in the code's descriptor. Units to report = dose given ÷ 50 mg. J-code billing units.

J8522 — Capecitabine, oral, 50 mg