No. J0561 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code.

What NDCs are billed under J0561?

CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 5 NDCs under J0561, for Bicillin L-A. The table on this page shows each one with its billing units per package.

What is the Medicare payment limit for J0561?

$25.612 per 100,000 units, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

What is one billing unit of J0561?

One unit of J0561 is 000 units, as stated in the code's descriptor. Units to report = dose given ÷ 000 units.

J0561 J-Code: Bicillin L-A (penicillin g benzathine)

In short

J0561 is the HCPCS Level II code for injection, penicillin g benzathine, 100,000 units. CMS assigns NDCs for Bicillin L-A to it. One billing unit is 000 units. The Medicare Part B payment limit is $25.612 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file

HCPCS codeJ0561

Billing unit000 units

Descriptor: Injection, penicillin g benzathine, 100,000 units
Short descriptor: Penicillin g benzathine inj
Code set: HCPCS Level II, maintained by CMS
Effective: Jan 1, 2016

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$25.612

Per100,000 units

Coinsurance15.105%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: Inflation-adjusted coinsurance. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Units = dose given ÷ 000 units. For example, 0 units is units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

HCPCS units

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the units to build the claim line.

NDCs billed under J0561

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 5 NDCs to J0561 for Bicillin L-A. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J0561 in the CMS ASP crosswalk
Drug	NDC (11-digit)	Labeler	Package	Billing units per package
Bicillin L-A	50090-1016-00	A-S Medication Solutions	10 × 2	120
Bicillin L-A	50090-1016-01	A-S Medication Solutions	2	12
Bicillin L-A	60793-0700-10	Pfizer Inc	10 × 1	60
Bicillin L-A	60793-0701-10	Pfizer Inc	10 × 2	120
Bicillin L-A	60793-0702-10	Pfizer Inc	10 × 4	240

J0561: common questions

Is J0561 a CPT code?: No. J0561 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J0561?: CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 5 NDCs under J0561, for Bicillin L-A. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J0561?: $25.612 per 100,000 units, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
What is one billing unit of J0561?: One unit of J0561 is 000 units, as stated in the code's descriptor. Units to report = dose given ÷ 000 units. J-code billing units.

J0561 — Injection, penicillin g benzathine, 100,000 units