HCPCS Level II drug code
J1271 — Injection, doxycycline hyclate, 1 mg
In short
J1271 is the HCPCS Level II code for injection, doxycycline hyclate, 1 mg. CMS assigns NDCs for Doxycycline Hyclate to it. One billing unit is 1 mg. The Medicare Part B payment limit is $0.081 per unit (October 1, 2026 through December 31, 2026).
Code
CMS HCPCS file- Descriptor
- Injection, doxycycline hyclate, 1 mg
- Short descriptor
- Inj doxycycline hyclate 1 mg
- Code set
- HCPCS Level II, maintained by CMS
- Effective
- Apr 1, 2025
The billing unit is read from the descriptor. Confirm it against the CMS file before billing.
Medicare Part B payment limit
CMS ASP fileEffective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files
Units and claim line
Units = dose given ÷ 1 mg. For example, 100 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.
Enter the dose given to build the claim line.
NDCs billed under J1271
CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 17 NDCs to J1271 for Doxycycline Hyclate. Billing units per package are CMS’s figures for this code’s unit.
| Drug | NDC (11-digit) | Labeler | Package | Billing units per package |
|---|---|---|---|---|
| Doxycycline Hyclate | 00143-9381-10 | Hikma Pharmaceuticals USA Inc. | 10 × 1 | 1,000 |
| Doxycycline Hyclate | 00404-9855-99 | Henry Schein Inc. | 1 | 100 |
| Doxycycline Hyclate | 42023-0244-10 | Endo USA, Inc. | 10 × 1 | 1,000 |
| Doxycycline Hyclate | 43598-0086-58 | Dr. Reddy's Laboratories Inc. | 10 × 1 | 1,000 |
| Doxycycline Hyclate | 51662-1402-01 | HF Acquisition Co. LLC, DBA HealthFirst | 1 | 100 |
| Doxycycline Hyclate | 51662-1402-03 | HF Acquisition Co. LLC, DBA HealthFirst | 10 × 1 | 1,000 |
| Doxycycline Hyclate | 63323-0130-11 | FreseniUS Kabi USA, LLC | 10 × 1 | 1,000 |
| Doxycycline Hyclate | 63323-0130-13 | FreseniUS Kabi USA, LLC | 10 × 1 | 1,000 |
| Doxycycline Hyclate | 63323-0130-17 | FreseniUS Kabi USA, LLC | 10 × 1 | 1,000 |
| Doxycycline Hyclate | 66794-0237-41 | Piramal Critical Care Inc | 10 × 1 | 1,000 |
| Doxycycline Hyclate | 67457-0437-10 | Mylan Institutional LLC | 10 × 1 | 1,000 |
| Doxycycline Hyclate | 68382-0910-10 | Zydus Pharmaceuticals (USA) Inc. | 10 × 1 | 1,000 |
| Doxycycline Hyclate | 70436-0032-82 | Slate Run Pharmaceuticals | 10 × 1 | 1,000 |
| Doxycycline Hyclate | 70748-0338-10 | Lupin Pharmaceuticals, Inc. | 10 × 1 | 1,000 |
| Doxycycline Hyclate | 71288-0030-21 | Meitheal Pharmaceuticals Inc. | 10 × 1 | 1,000 |
| Doxycycline Hyclate | 72266-0237-05 | Fosun Pharma USA Inc. | 5 × 1 | 500 |
| Doxycycline Hyclate | 83634-0111-20 | Avenacy Inc. | 10 × 1 | 1,000 |
J1271: common questions
- Is J1271 a CPT code?
- No. J1271 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
- What NDCs are billed under J1271?
- CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 17 NDCs under J1271, for Doxycycline Hyclate. The table on this page shows each one with its billing units per package.
- What is the Medicare payment limit for J1271?
- $0.081 per 1 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
- What is one billing unit of J1271?
- One unit of J1271 is 1 mg, as stated in the code's descriptor. Units to report = dose given ÷ 1 mg. J-code billing units.