In short

J2315 is the HCPCS Level II code for injection, naltrexone, depot form, 1 mg. CMS assigns NDCs for Vivitrol to it. One billing unit is 1 mg. The Medicare Part B payment limit is $4.537 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file
HCPCS codeJ2315
Billing unit1 mg
Descriptor
Injection, naltrexone, depot form, 1 mg
Short descriptor
Naltrexone, depot form
Code set
HCPCS Level II, maintained by CMS
Effective
Jan 1, 2007

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$4.537
Per1 mg
Coinsurance19.283%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: Inflation-adjusted coinsurance. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Units = dose given ÷ 1 mg. For example, 100 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

NDCs billed under J2315

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 1 NDC to J2315 for Vivitrol. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J2315 in the CMS ASP crosswalk
DrugNDC (11-digit)LabelerPackageBilling units per package
Vivitrol65757-0300-01Alkermes, Inc.1380

J2315: common questions

Is J2315 a CPT code?
No. J2315 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J2315?
CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 1 NDC under J2315, for Vivitrol. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J2315?
$4.537 per 1 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
What is one billing unit of J2315?
One unit of J2315 is 1 mg, as stated in the code's descriptor. Units to report = dose given ÷ 1 mg. J-code billing units.

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