In short

J3470 is the HCPCS Level II code for injection, hyaluronidase, up to 150 units. CMS assigns NDCs for Amphadase to it. The Medicare Part B payment limit is $31.802 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file
HCPCS codeJ3470
Billing unitSee descriptor
Descriptor
Injection, hyaluronidase, up to 150 units
Short descriptor
Hyaluronidase injection
Code set
HCPCS Level II, maintained by CMS
Effective
Jan 1, 1997

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$31.802
Per150 units
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Enter the units to build the claim line.

NDCs billed under J3470

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 1 NDC to J3470 for Amphadase. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J3470 in the CMS ASP crosswalk
DrugNDC (11-digit)LabelerPackageBilling units per package
Amphadase00548-9090-10Amphastar Pharmaceuticals, Inc.10 × 110

J3470: common questions

Is J3470 a CPT code?
No. J3470 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J3470?
CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 1 NDC under J3470, for Amphadase. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J3470?
$31.802 per 150 units, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

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