In short

J8560 is the HCPCS Level II code for etoposide; oral, 50 mg. CMS assigns NDCs for Etoposide to it. One billing unit is 50 mg. The Medicare Part B payment limit is $88.164 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file
HCPCS codeJ8560
Billing unit50 mg
Descriptor
Etoposide; oral, 50 mg
Short descriptor
Etoposide oral 50 mg
Code set
HCPCS Level II, maintained by CMS

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$88.164
Per50 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Units = dose given ÷ 50 mg. For example, 5000 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

NDCs billed under J8560

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 1 NDC to J8560 for Etoposide. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J8560 in the CMS ASP crosswalk
DrugNDC (11-digit)LabelerPackageBilling units per package
Etoposide00378-3266-94Mylan Pharmaceuticals Inc.2020

J8560: common questions

Is J8560 a CPT code?
No. J8560 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J8560?
CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 1 NDC under J8560, for Etoposide. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J8560?
$88.164 per 50 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
What is one billing unit of J8560?
One unit of J8560 is 50 mg, as stated in the code's descriptor. Units to report = dose given ÷ 50 mg. J-code billing units.

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