In short

J9181 is the HCPCS Level II code for injection, etoposide, 10 mg. One billing unit is 10 mg.

J9181 ends on Sep 30, 2026

CMS is discontinuing J9181; it can’t be reported for dates of service after Sep 30, 2026.

Code

CMS HCPCS file
HCPCS codeJ9181
Billing unit10 mg
Descriptor
Injection, etoposide, 10 mg
Short descriptor
Etoposide injection
Code set
HCPCS Level II, maintained by CMS
Effective
Oct 1, 2026

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Units and claim line

Units = dose given ÷ 10 mg. For example, 1000 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Find the NDC

Med-Code hasn’t mapped J9181 to specific products yet. Search the FDA NDC Directory for the drug named in the descriptor, and check the route and strength match the code.

Search NDCs for etoposide

J9181: common questions

Is J9181 a CPT code?
No. J9181 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What is one billing unit of J9181?
One unit of J9181 is 10 mg, as stated in the code's descriptor. Units to report = dose given ÷ 10 mg. J-code billing units.

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