Differin (adapalene) NDC 0299-4910

NDC codes

FDA NDC Directory

Product NDC (as listed)0299-4910Labeler and product segments. Claims need a package NDC.

Product NDC at billing width00299-4910Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
0299-4910-00	00299491000	1 TUBE in 1 BLISTER PACK (0299-4910-00) / 2 g in 1 TUBEMarketed from Jul 8, 2016
0299-4910-10	00299491010	1 BOTTLE, PUMP in 1 CARTON (0299-4910-10) / 15 g in 1 BOTTLE, PUMPMarketed from Jan 1, 2020
0299-4910-15	00299491015	1 TUBE in 1 CARTON (0299-4910-15) / 15 g in 1 TUBEMarketed from Jul 8, 2016
0299-4910-40	00299491040	1 BOTTLE, PUMP in 1 CARTON (0299-4910-40) / 45 g in 1 BOTTLE, PUMPMarketed from Jan 1, 2020
0299-4910-45	00299491045	1 TUBE in 1 CARTON (0299-4910-45) / 45 g in 1 TUBEMarketed from Jul 8, 2016

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Differin
Generic name (nonproprietary): adapalene
Active ingredients: Adapalene — 1 mg/g
Dosage form: Gel
Route: Topical
Labeler: Galderma Laboratories, L.P.
Product type: Over-the-counter drug
Marketing category: NDA — New Drug ApplicationApplication NDA 020380
Marketing start: Jul 8, 2016
Listing expires: Dec 31, 2026
Other FDA classes: Retinoids (Chemical structure)
Identifiers: Product ID 0299-4910_7d2ef345-753e-4f6c-bb76-15fae398a44dSPL ID 7d2ef345-753e-4f6c-bb76-15fae398a44dSPL set ID 0739d631-171b-42a8-bd55-0022b8df2d8aRxCUI 153183, 307731UNII 1L4806J2QF
Pharmacologic class: Retinoid

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N400299491000 followed by a unit qualifier and the quantity

Package 00299-4910-00. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Dec 7, 2022.

Indications (excerpt from the label)

Use For the treatment of acne

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)