What is NDC 21922-096?

21922-096 is the product NDC for Hydrocortisone, Hydrocortisone 1 g/100g cream, listed with the FDA by Encube Ethicals, Inc.. It has 2 package NDCs, shown above in 10- and 11-digit form.

Encube Ethicals, Inc., NDC labeler code 21922. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Hydrocortisone?

169 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Hydrocortisone NDC 21922-096 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)21922-096Labeler and product segments. Claims need a package NDC.

Product NDC at billing width21922-0096Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
21922-096-04	21922009604	1 TUBE in 1 CARTON (21922-096-04) / 14 g in 1 TUBEMarketed from Feb 25, 2025
21922-096-05	21922009605	1 TUBE in 1 CARTON (21922-096-05) / 28 g in 1 TUBEMarketed from Feb 25, 2025

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Hydrocortisone
Generic name (nonproprietary): hydrocortisone
Active ingredients: Hydrocortisone — 1 g/100g
Dosage form: Cream
Route: Topical
Labeler: Encube Ethicals, Inc.NDC labeler code 21922
Product type: Over-the-counter drug
Marketing category: OTC monograph drugApplication M 017
Marketing start: Feb 25, 2025
Listing expires: Dec 31, 2026
Other FDA classes: Corticosteroid Hormone Receptor Agonists (Mechanism)
Identifiers: Product ID 21922-096_00f13ac4-5e1e-4ff8-8a9f-50a7c272ea20SPL ID 00f13ac4-5e1e-4ff8-8a9f-50a7c272ea20SPL set ID 969cd576-82d3-4662-bbc1-3587a1f6a564RxCUI 106258UNII WI4X0X7BPJUPC 0321922096057
Pharmacologic class: Corticosteroid

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N421922009604 followed by a unit qualifier and the quantity

Package 21922-0096-04. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Nov 10, 2025.

Indications (excerpt from the label)

USE(S) ■temporarily relieves itching associated with minor skin irritations, inflammation, and rashes due to ■eczema ■ psoriasis ■ insect bites ■ poison ivy, oak, sumac ■detergents ■ jewelry ■ cosmetics ■ soaps ■ seborrheic dermatitis ■temporarily relieves external anal and genital itching ■other uses of this product should be only under the advice and supervision of a doctor

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 21922-096

What is NDC 21922-096?: 21922-096 is the product NDC for Hydrocortisone, Hydrocortisone 1 g/100g cream, listed with the FDA by Encube Ethicals, Inc.. It has 2 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Hydrocortisone.
What is the active ingredient?: Hydrocortisone.
Who is the labeler?: Encube Ethicals, Inc., NDC labeler code 21922. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Hydrocortisone?: 169 other product NDCs are listed under this name. See all Hydrocortisone NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Hydrocortisone NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Hydrocortisone	Hydrocortisone 1 g/100g	LotionTopical	Amazon.com Services LLC	72288-469	72288-0469-25
Hydrocortisone	Hydrocortisone 5 mg/1	TabletOral	Solco Healthcare LLC	43547-892	43547-0892-05
Hydrocortisone	Hydrocortisone 10 mg/1	TabletOral	Solco Healthcare LLC	43547-893	43547-0893-10
Hydrocortisone	Hydrocortisone 20 mg/1	TabletOral	Solco Healthcare LLC	43547-894	43547-0894-10
Hydrocortisone	Hydrocortisone 1 g/100g	CreamTopical	Amazon.com Services LLC	72288-713	72288-0713-64
Hydrocortisone	Hydrocortisone 25 mg/g	CreamTopical	Encube Ethicals, Inc.	21922-065	21922-0065-0521922-0065-30
Hydrocortisone	Hydrocortisone 20 mg/g	GelTopical	Redmont Pharmaceuticals, LLC	71741-455	71741-0455-31
Hydrocortisone	Hydrocortisone 10 mg/g	CreamTopical	Sportpharm LLC	85766-166	85766-0166-1085766-0166-25
hydrocortisone	Hydrocortisone 1 g/100g	CreamTopical	Sportpharm LLC	85766-151	85766-0151-28
Hydrocortisonehydrocortisone cream 1%	Hydrocortisone 1 g/100g	CreamTopical	Aldermed Inc.	87236-004	87236-0004-09

All 170 Hydrocortisone NDCs

Other NDCs under M 017

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under M 017
Product	Strength	Form · route	Labeler	Product NDC
Rite Aid Hydrocortisonehydrocortisone 1%	Hydrocortisone 1 g/100g	OintmentTopical	Rite Aid	11822-2685
Flanaxmethyl salicylate, menthol, capsaicin	Methyl salicylate 28 g/100g + 2 more ingredients	LinimentTopical	Belmora LLC	27854-499
Profoot Pain Relief Patchescamphor, menthol, methyl salicylate	—	Kit	Rooftop Consumer Health, Inc.	29784-600
Eagle Medicatedmenthol methyl salicylate	Methyl salicylate 30 g/100mL; Menthol 14.5 g/100mL	OilTopical	Borden Company (Private) Limited	43405-008
Burn Relief Aloelidocaine hcl	Lidocaine hydrochloride 4 g/100g	GelTopical	Acutens	80551-001
Large Pain Relievingcamphor menthol methyl salicytate	Camphor (Synthetic) 3.1 g/100g + 2 more ingredients	PatchTopical	Walgreen Company	0363-9904
Teeter Renew Muscles Pain Relievingmethyl salicylate, menthol	Methyl salicylate 100 mg/mL; Menthol 70 mg/mL	CreamTopical	STL International INC	70329-730
Nufabrx Medicine Infused Sockscapsaicin	Capsaicin .12 g/100g	ClothTopical	Nufabrx LLC	72490-037
Burnlidocaine	Lidocaine hydrochloride 2 mg/100mL	SprayTopical	HART Health	50332-0210
Pramoxine Itch reliefpramoxine hcl 1%	Pramoxine hydrochloride 1 g/100g	CreamTopical	CVS	51316-141
DG Health Hydrocortisone Maximum Strengthhydrocortisone	Hydrocortisone 1 g/100g	CreamTopical	Dolgencorp Inc	55910-319
Methyl Salicylate 10% Pain Relievingmethyl salicylate	Methyl salicylate 100 mg/g	CreamTopical	PureTek Corporation	59088-243
Biofreezementhol	Menthol 105 mg/mL	SprayTopical	Reckitt Benckiser LLC	59316-833
Qr Painanalgesic	Mannitol 30 g/100g; Menthol 1.25 g/100g	CreamTopical	MARYHELENE ENTERPRISES INC	73180-005
Methyl Salicylate 25% Creammethyl salicylate	Methyl salicylate 250 mg/mL	CreamTopical	Medcore LLC	82461-415
Profoot Pain Relief Patchescamphor, menthol, methyl salicylate	—	Kit	Profoot, Inc.	29784-601
Lidocaineburn relief	Lidocaine .64 g/127g	Aerosol, SprayTopical	Foodhold USA	41520-162
Eagle Medicated Aromaticcamphor menthol methyl salicylate	Camphor (Synthetic) 7 g/100mL + 2 more ingredients	OilTopical	Borden Company (Private) Limited	43405-009
Hydrocortisone	Hydrocortisone 10 mg/g	CreamTopical	Unifirst First Aid Corporation	47682-933
Arctic Heatmenthol, methyl salicylate	Methyl salicylate 11.2 g/112g; Menthol 2.24 g/112g	CreamTopical	Renu Laboratories, LLC	76348-414

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