HCPCS drug code · CMS crosswalk
Tyzavan J-Code / HCPCS Code
In short
Tyzavan is billed under HCPCS J3375 — Injection, vancomycin hydrochloride (tyzavan), not therapeutically equivalent to j3373, 10 mg. One billing unit is 10 mg. CMS's crosswalk lists 7 Tyzavan NDCs under this code.
Reference
- J3375
- Injection, vancomycin hydrochloride (tyzavan), not therapeutically equivalent to j3373, 10 mgBilling unit: 10 mg
- Labelers
- Hikma Pharmaceuticals USA Inc.
Medicare Part B payment limit
CMS ASP fileEffective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files
Tyzavan units and claim line
Enter the dose given to get the J3375 units and the NDC line for the CMS-1500 and the 837P.
Enter the dose given to build the claim line.
Tyzavan NDCs and billing units
From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.
| NDC (11-digit) | HCPCS | Labeler | Package | Billing units per package |
|---|---|---|---|---|
| 00143-9466-06 | J3375 | Hikma Pharmaceuticals USA Inc. | 6 × 250 | 750 |
| 00143-9467-06 | J3375 | Hikma Pharmaceuticals USA Inc. | 6 × 350 | 1050 |
| 00143-9468-12 | J3375 | Hikma Pharmaceuticals USA Inc. | 12 × 150 | 900 |
| 00143-9469-06 | J3375 | Hikma Pharmaceuticals USA Inc. | 6 × 300 | 900 |
| 00143-9470-06 | J3375 | Hikma Pharmaceuticals USA Inc. | 6 × 400 | 1200 |
| 00143-9471-12 | J3375 | Hikma Pharmaceuticals USA Inc. | 12 × 100 | 600 |
| 00143-9472-12 | J3375 | Hikma Pharmaceuticals USA Inc. | 12 × 200 | 1200 |
Tyzavan: common questions
- What is the J-code for Tyzavan?
- Tyzavan is billed under HCPCS J3375 — Injection, vancomycin hydrochloride (tyzavan), not therapeutically equivalent to j3373, 10 mg. One billing unit is 10 mg. CMS's crosswalk lists 7 Tyzavan NDCs under this code.
- How many J3375 billing units are in a package of Tyzavan?
- CMS lists 600 to 1,200 billing units per package, depending on the NDC, where one unit is 10 mg. Units to report are based on the dose given, not the package.
- Is J3375 a CPT code?
- No. J3375 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.