In short

J3376 is the HCPCS Level II code for injection, vancomycin hcl (hikma), not therapeutically equivalent to j3373, 10 mg. CMS assigns NDCs for Vancomycin HCl to it. One billing unit is 10 mg. The Medicare Part B payment limit is $0.016 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file
HCPCS codeJ3376
Billing unit10 mg
Descriptor
Injection, vancomycin hcl (hikma), not therapeutically equivalent to j3373, 10 mg
Short descriptor
Inj vancomycin (hikma) 10mg
Code set
HCPCS Level II, maintained by CMS
Effective
Jan 1, 2026

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.016
Per10 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Units = dose given ÷ 10 mg. For example, 1000 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

NDCs billed under J3376

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 5 NDCs to J3376 for Vancomycin HCl. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J3376 in the CMS ASP crosswalk
DrugNDC (11-digit)LabelerPackageBilling units per package
Vancomycin HCl00143-9161-10Hikma Pharmaceuticals USA Inc.10 × 1500
Vancomycin HCl00143-9161-25Hikma Pharmaceuticals USA Inc.25 × 11,250
Vancomycin HCl00143-9162-10Hikma Pharmaceuticals USA Inc.10 × 11,000
Vancomycin HCl00143-9163-01Hikma Pharmaceuticals USA Inc.1500
Vancomycin HCl00143-9164-01Hikma Pharmaceuticals USA Inc.11,000

J3376: common questions

Is J3376 a CPT code?
No. J3376 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J3376?
CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 5 NDCs under J3376, for Vancomycin HCl. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J3376?
$0.016 per 10 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
What is one billing unit of J3376?
One unit of J3376 is 10 mg, as stated in the code's descriptor. Units to report = dose given ÷ 10 mg. J-code billing units.

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