In short

J3374 is the HCPCS Level II code for injection, vancomycin hydrochloride (mylan) not therapeutically equivalent to j3373, 10 mg. CMS assigns NDCs for Vancomycin HCl to it. One billing unit is 10 mg. The Medicare Part B payment limit is $0.091 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file
HCPCS codeJ3374
Billing unit10 mg
Descriptor
Injection, vancomycin hydrochloride (mylan) not therapeutically equivalent to j3373, 10 mg
Short descriptor
Inj, vancomycin (mylan) 10mg
Code set
HCPCS Level II, maintained by CMS
Effective
Jul 1, 2025

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.091
Per10 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Units = dose given ÷ 10 mg. For example, 1000 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

NDCs billed under J3374

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 17 NDCs to J3374 for Vancomycin HCl. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J3374 in the CMS ASP crosswalk
DrugNDC (11-digit)LabelerPackageBilling units per package
Vancomycin HCl00143-9152-10Hikma Pharmaceuticals USA Inc.10 × 11,250
Vancomycin HCl00143-9153-10Hikma Pharmaceuticals USA Inc.10 × 11,500
Vancomycin HCl25021-0147-20Sagent Pharmaceuticals10 × 1750
Vancomycin HCl25021-0148-30Sagent Pharmaceuticals10 × 11,250
Vancomycin HCl25021-0149-30Sagent Pharmaceuticals10 × 11,500
Vancomycin HCl39822-0460-02XGen Pharmaceuticals DJB, Inc.10 × 11,250
Vancomycin HCl39822-0470-02XGen Pharmaceuticals DJB, Inc.10 × 11,500
Vancomycin HCl55150-0471-10Eugia US LLC10 × 11,250
Vancomycin HCl55150-0472-10Eugia US LLC10 × 11,500
Vancomycin HCl67457-0705-75Mylan Institutional LLC10 × 1750
Vancomycin HCl67457-0823-99Mylan Institutional LLC10 × 11,250
Vancomycin HCl67457-0824-99Mylan Institutional LLC10 × 11,500
Vancomycin HCl68462-0477-74Glenmark Pharmaceuticals Inc., USA10 × 1750
Vancomycin HCl68462-0478-84Glenmark Pharmaceuticals Inc., USA10 × 11,250
Vancomycin HCl68462-0479-84Glenmark Pharmaceuticals Inc., USA10 × 11,500
Vancomycin HCl72078-0065-99Mylan Institutional LLC10 × 11,750
Vancomycin HCl72078-0066-99Mylan Institutional LLC10 × 12,000

J3374: common questions

Is J3374 a CPT code?
No. J3374 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J3374?
CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 17 NDCs under J3374, for Vancomycin HCl. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J3374?
$0.091 per 10 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
What is one billing unit of J3374?
One unit of J3374 is 10 mg, as stated in the code's descriptor. Units to report = dose given ÷ 10 mg. J-code billing units.

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