J8521 was retired on Sep 30, 2024

CMS ended J8521 after Sep 30, 2024. Don’t report it for later dates of service. Current codes for the same drug:

Code

CMS HCPCS file
HCPCS codeJ8521
Billing unit500 mg
Descriptor
Capecitabine, oral, 500 mg
Short descriptor
Capecitabine, oral, 500 mg
Code set
HCPCS Level II, maintained by CMS
Effective
Oct 1, 2024

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

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Med-Code hasn’t mapped J8521 to specific products yet. Search the FDA NDC Directory for the drug named in the descriptor, and check the route and strength match the code.

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J8521: common questions

Is J8521 a CPT code?
No. J8521 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What is one billing unit of J8521?
One unit of J8521 is 500 mg, as stated in the code's descriptor. Units to report = dose given ÷ 500 mg. J-code billing units.

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