J2310 was retired on Jun 30, 2025

CMS ended J2310 after Jun 30, 2025. Don’t report it for later dates of service. Current codes for the same drug:

Code

CMS HCPCS file
HCPCS codeJ2310
Billing unit1 mg
Descriptor
Injection, naloxone hydrochloride, per 1 mg
Short descriptor
Inj naloxone hydrochloride
Code set
HCPCS Level II, maintained by CMS
Effective
Jul 1, 2025

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Find the NDC

Med-Code hasn’t mapped J2310 to specific products yet. Search the FDA NDC Directory for the drug named in the descriptor, and check the route and strength match the code.

Search NDCs for naloxone hydrochloride

J2310: common questions

Is J2310 a CPT code?
No. J2310 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What is one billing unit of J2310?
One unit of J2310 is 1 mg, as stated in the code's descriptor. Units to report = dose given ÷ 1 mg. J-code billing units.

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