HCPCS Level II drug codes
J-Code List & Lookup
Every HCPCS drug code with its descriptor and billing unit. Look up a code by number or drug name; each code page lists the NDCs CMS assigns to it.
From the CMS HCPCS Level II file
Codes and descriptors come from HCPC2026_OCT_ANWEB_09232026.xlsx, the CMS quarterly HCPCS file. HCPCS Level II is maintained by CMS and updated quarterly — confirm a code in the current CMS HCPCS files before billing. October 2026 code changes · What is a J-code?
All J-codes
22 codes starting J8
| Code | Descriptor | Billing unit | Drugs |
|---|---|---|---|
| J8498 | Antiemetic drug, rectal/suppository, not otherwise specified | No defined unit | — |
| J8499 | Prescription drug, oral, non chemotherapeutic, nos | See descriptor | — |
| J8501 | Aprepitant, oral, 5 mg | 5 mg | Aprepitant, Emend |
| J8502 | Injection, aprepitant (aponvie), 1 mg | 1 mg | Aponvie |
| J8510 | Busulfan; oral, 2 mg | 2 mg | — |
| J8515 | Cabergoline, oral, 0.25 mg | 0.25 mg | Cabergoline |
| J8522 | Capecitabine, oral, 50 mg | 50 mg | Capecitabine, Xeloda |
| J8530 | Cyclophosphamide; oral, 25 mg | 25 mg | Cyclophosphamide |
| J8540 | Dexamethasone, oral, 0.25 mg | 0.25 mg | Dexamethasone, Dexamethasone Intensol |
| J8541 | Dexamethasone (hemady), oral, 0.25 mg | 0.25 mg | Hemady |
| J8560 | Etoposide; oral, 50 mg | 50 mg | Etoposide |
| J8565 | Gefitinib, oral, 250 mg | 250 mg | — |
| J8597 | Antiemetic drug, oral, not otherwise specified | No defined unit | — |
| J8600 | Melphalan; oral, 2 mg | 2 mg | — |
| J8610 | Methotrexate; oral, 2.5 mg | 2.5 mg | Methotrexate, Trexall |
| J8611 | Methotrexate (jylamvo), oral, 2.5 mg | 2.5 mg | Jylamvo |
| J8612 | Methotrexate (xatmep), oral, 2.5 mg | 2.5 mg | Xatmep |
| J8655 | Netupitant 300 mg and palonosetron 0.5 mg, oral | See descriptor | Akynzeo |
| J8670 | Rolapitant, oral, 1 mg | 1 mg | — |
| J8700 | Temozolomide, oral, 5 mg | 5 mg | Temozolomide |
| J8705 | Topotecan, oral, 0.25 mg | 0.25 mg | Hycamtin |
| J8999 | Prescription drug, oral, chemotherapeutic, nos | See descriptor | — |
CPT vaccine product codes
Vaccines are reported with a CPT product code rather than a J-code, plus a separate immunization administration code. Descriptions here are Med-Code’s own; CPT descriptors are licensed by the AMA.
| Code | Descriptor | Billing unit | Drugs in directory | Type |
|---|---|---|---|---|
| CPT 90651 | Vaccine product code for GARDASIL 9 (human papillomavirus 9-valent vaccine) | 1 dose | Gardasil 9 | CPT vaccine product |
| CPT 90677 | Vaccine product code for PREVNAR 20 (pneumococcal 20-valent conjugate vaccine) | 1 dose | Prevnar 20 | CPT vaccine product |
| CPT 90678 | Vaccine product code for ABRYSVO (respiratory syncytial virus vaccine, bivalent) | 1 dose | Abrysvo | CPT vaccine product |
| CPT 90679 | Vaccine product code for AREXVY (respiratory syncytial virus vaccine, adjuvanted) | 1 dose | Arexvy | CPT vaccine product |
| CPT 90750 | Vaccine product code for SHINGRIX (zoster vaccine recombinant, adjuvanted) | 1 dose | Shingrix | CPT vaccine product |
By therapeutic category
- Analgesic / Antipyretic1 code
- Antibiotic / Cephalosporin1 code
- Antiemetic / 5-HT31 code
- Autoimmune / Anti-TNF2 codes
- Bone Health / RANKL1 code
- Chemotherapy / CD20 Biologic1 code
- Chemotherapy / CD38 Biologic1 code
- Chemotherapy / HER2 Biologic1 code
- Chemotherapy / Immunotherapy2 codes
- Chemotherapy / PD-L1 Biologic2 codes
- Chemotherapy / VEGF Biologic1 code
- Colony Stimulating Factor1 code
- Contraceptive / Progestin1 code
- Corticosteroid1 code
- Gastroenterology / Integrin1 code
- GIP / GLP-1 Dual Agonist1 code
- GLP-1 Receptor Agonist1 code
- Hematologic / IV Iron1 code
- Immunology / IL-12/231 code
- Immunology / IL-4/131 code
- Neuromuscular Blocker / Toxin1 code
- Ophthalmic / Ang-2 & VEGF1 code
- Ophthalmic / Anti-VEGF2 codes
- Sympathomimetic / Anaphylaxis1 code
- Vaccine / Immunization5 codes
Find a J-code by drug name
1,087 brand and generic names, each with its code and billing unit. All drugs A–Z.